منابع مشابه
Modeling non-heme iron proteins.
Synthetic modeling studies of non-heme iron proteins continue to contribute to our understanding of the mechanism of these proteins. Recently, mononuclear Fe(IV)=O complexes have been prepared and characterized to model the same species that are proposed to be the reactive intermediates in reactions involving mononuclear non-heme iron proteins. Generation of such species for the oxidation of or...
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Dynamic Bayesian networks (DBNs) are increasingly adopted as tools for the modeling of dynamic domains involving uncertainty. Due to their ease of modeling, repetitive DBNs are the standard. However, repetitive DBNs do not allow the independence relations to vary over time. In contrast, non-repetitive DBNs do allow for modeling time-varying relations, but are hard to apply to dynamic domains du...
متن کاملInterfacial Rheology of Globular Proteins
Protein-surfactant mixtures appear in many industrial and biological applications. Indeed, a fluid as vital as blood contains a mixture of serum albumin proteins with various other smaller surface-active components. Proteins and other surface active molecules are often adsorbed at an air-liquid or liquid-liquid interface due to favorable thermodynamics, and these interfaces play a role in such ...
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Protein crystallization, aggregation, liquid-liquid phase separation, and self-assembly are important in protein structure determination in the industrial processing of proteins and in the inhibition of protein condensation diseases. To fully describe such phase transformations in globular protein solutions, it is necessary to account for the strong spatial variation of the interactions on the ...
متن کاملFolding units in globular proteins.
We present a method to identify all compact, contiguous-chain, structural units in a globular protein from x-ray coordinates. These units are then used to describe a complete set of hierarchic folding pathways for the molecule. Our analysis shows that the larger units are combinations of smaller units, giving rise to a structural hierarchy ranging from the whole protein monomer through supersec...
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ژورنال
عنوان ژورنال: Protein Science
سال: 2016
ISSN: 0961-8368
DOI: 10.1002/pro.2907